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Concrete accounts for about 8% of the world's greenhouse gas emissions, notes CNN. But a research team at the University of Pennsylvania just used a robotic 3D printer to construct a bridge with "complex, lattice-like patterns" that are just as strong and durable — but with materials that absorb more carbon dioxide. Check out the photos of the "Diamanti" projects "post-tensioned concrete canopy". And CNN's report includes an animated photo showing the 3D printer in action: While most regular concrete absorbs carbon dioxide (up to 30% of its production emissions over its entire life cycle, according to some research), Diamanti's enhanced concrete mixture absorbs 142% more carbon dioxide than conventional concrete mixes. Its first design, a pedestrian bridge, uses 60% less material while retaining mechanical strength, says Masoud Akbarzadeh, an associate professor of architecture at the University of Pennsylvania and director of the lab that spearheaded the project. "Through millions of years of evolution, nature has learned that you don't need material everywhere," says Akbarzadeh. "If you take a cross section of a bone, you realize that bone is quite porous, but there are certain patterns within which the load (or weight) is transferred." By mimicking the structures in certain porous bones — known as triply periodic minimal surface (TPMS) structures — âDiamanti also increased the surface area of the bridge, increasing the concrete mixture's carbon absorption potential by another 30%... According to Akbarzadeh, 3D printing reduces construction time, material, and energy use by 25%, and its structural system reduces the need for steel by 80%, minimizing use of another emissions-heavy material. He added that using the technique with Diamanti's concrete significantly cuts greenhouse gas emissions compared to regular construction techniques, and reduces construction costs by 25% to 30%. "Even without the material innovation, the higher surface itself allows higher CO2 absorption," one engineering lecturer tells CNN. The project was a collaboration with chemical company Sika, funded with grants from the U.S. Energy Department, and is now preparing its first full-size prototype in France. The team has published their findings in the journal Advanced Functional Materials earlier this year.

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The James Webb Space Telescope gets its highest resolution with the aperture masking interferometer (or AMI), "a tiny piece of precisely machined metal that slots into one of the telescope's cameras," according to a new article by Benjamin Pope, an associated math professor at Macquarie University. "We can finally present its first successful observations of stars, planets, moons and even black hole jets." [AMI] was put on Webb to diagnose and measure any blur in its images. Even nanometres of distortion in Webb's 18 hexagonal primary mirrors and many internal surfaces will blur the images enough to hinder the study of planets or black holes, where sensitivity and resolution are key. AMI filters the light with a carefully structured pattern of holes in a simple metal plate, to make it much easier to tell if there are any optical misalignments. We wanted to use this mode to observe the birth places of planets, as well as material being sucked into black holes. But before any of this, AMI showed Webb wasn't working entirely as hoped. At very fine resolution — at the level of individual pixels — all the images were slightly blurry due to an electronic effect: brighter pixels leaking into their darker neighbours. This is not a mistake or flaw, but a fundamental feature of infrared cameras that turned out to be unexpectedly serious for Webb. This was a dealbreaker for seeing distant planets many thousands of times fainter than their stars a few pixels away: my colleagues quickly showed that its limits were more than ten times worse than hoped. So, we set out to correct it... We built a computer model to simulate AMI's optical physics, with flexibility about the shapes of the mirrors and apertures and about the colours of the stars. We connected this to a machine learning model to represent the electronics with an "effective detector model" — where we only care about how well it can reproduce the data, not about why. After training and validation on some test stars, this setup allowed us to calculate and undo the blur in other data, restoring AMI to full function. It doesn't change what Webb does in space, but rather corrects the data during processing. It worked beautifully — the star HD 206893 hosts a faint planet and the reddest-known brown dwarf (an object between a star and a planet). They were known but out of reach with Webb before applying this correction. Now, both little dots popped out clearly in our new maps of the system... With the new correction, we brought Jupiter's moon Io into focus, clearly tracking its volcanoes as it rotates over an hour-long timelapse. "This correction has opened the door to using AMI to prospect for unknown planets at previously impossible resolutions and sensitivities..." the article points out. "Our results on painstakingly testing and enhancing AMI are now released on the open-access archive arXiv in a pair of papers." Thanks to long-time Slashdot reader schwit1 for sharing the article.

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Canada's Prime Minister "paused an electric-vehicle sales mandate that was set to take effect next year," reports the Wall Street Journal, which argues a kind of retreat from electric-vehicle ambitions "is spreading around the globe." Even the U.K.'s Prime Minister "has allowed for a more flexible timetable to hit the country's EV targets." And demand is expected to drop in the U.S., where global consulting firm AlixPartners now predicts EVs will make up 18% of new-vehicle sales by 2030 — just half of what they'd predicted two years ago: j U.S. automaker GM will take a $1.6 billion charge "because of sinking EV sales," reports the Wall Street Journal, "a shift it blamed on recent moves by the U.S. government to end EV subsidies and regulatory mandates... That might just be the beginning of a financial reckoning from automakers that poured billions into new electric models — from sports cars and sedans to big pickups and sport-utility vehicles — to try to get ready for the government-backed EV mandates. Automakers have been saying that consumers aren't adopting EVs as quickly as expected, and government efforts to proliferate the technology are hammering their bottom lines. GM, in announcing its charge, said it is reassessing EV capacity and warned that more losses are possible...Carmakers argue the EV business model is an unprofitable proposition given still-high battery costs, spotty car-charging networks and dwindling government subsidies. Incentive programs have ended or have been pared back across Europe and in the U.S. and Canada. Volkswagen, burdened with massive electrification costs, helped spur the reckoning in Europe when it said it would cut 35,000 jobs as part of a deal with its union. The move sent shock waves through the region's political establishment. Weeks later, the EU launched a "strategic dialogue" with the automotive industry that led to a more flexible timetable for automakers to meet its emissions rules for 2025.

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In Reddit's "Family Medicine" subreddit, a moderator noticed earlier this week that the AI-powered "Reddit Answers" was automatically responding to posters, typically with "something related to what was posted." Unfortunately, that moderator says, Reddit Answers "has been spreading grossly dangerous misinformation."And yet Reddit's moderators "cannot disable this feature." Elsewhere a healthcare worker described what happened when they tested Reddit Answers: I made a post in r/familymedicine and a link appeared below it with information on treating chronic pain. The first post it cited urged people to stop their prescribed medications and take high-dose kratom which is an illegal (in some states) and unregulated substance. I absolutely do not endorse this... I also asked about the medical indications for heroin. One answer warned about addiction and linked to crisis and recovery resources. The other connects to a post where someone claims heroin saved their life and controls their chronic pain. The post was encouraging people to stop prescribed medications and use heroin instead. Heroin is a schedule I drug in the US which means there are no acceptable uses. It's incredibly addictive and dangerous. It is responsible for the loss of so many lives... The AI-generated answers could easily be mistaken as information endorsed by the sub it appears in. r/familymedicine absolutely does not endorse using heroin to treat chronic pain. This feature needs to be disabled in medical and mental health subs, or allow moderators of these subreddits to opt out. Better filters are also needed when users ask Reddit Answers health related questions. If this continues there will be adverse outcomes. People will be harmed. This needs to change. Two days ago an official Reddit "Admin" posted that "We've made some changes to where Answers appears based on this feedback," adding that beyond that Reddit "will continue to tweak based on what we're seeing and hearing." But the "Family Medicine" subreddit still has a top-of-page announcement warning every user there... "We do NOT and CANNOT endorse Reddit Answers at this time and urge every user of this sub to disregard anything it says."

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Cybercriminals are exploiting weak email authentication settings in Zendesk, using the platform's customer support systems to bombard targets with thousands of spam and harassing messages that appear to come from legitimate companies like The Washington Post, Discord, and NordVPN. KrebsOnSecurity reports: Zendesk is an automated help desk service designed to make it simple for people to contact companies for customer support issues. Earlier this week, KrebsOnSecurity started receiving thousands of ticket creation notification messages through Zendesk in rapid succession, each bearing the name of different Zendesk customers, such as CapCom, CompTIA, Discord, GMAC, NordVPN, The Washington Post, and Tinder. The abusive missives sent via Zendesk's platform can include any subject line chosen by the abusers. In my case, the messages variously warned about a supposed law enforcement investigation involving KrebsOnSecurity.com, or else contained personal insults. Moreover, the automated messages that are sent out from this type of abuse all come from customer domain names -- not from Zendesk. [...] In all of the cases above, the messaging abuse would not have been possible if Zendesk customers validated support request email addresses prior to sending responses. Failing to do so may make it easier for Zendesk clients to handle customer support requests, but it also allows ne'er-do-wells to sully the sender's brand in service of disruptive and malicious email floods. "We recognize that our systems were leveraged against you in a distributed, many-against-one manner," said Carolyn Camoens, communications director at Zendesk. "We are actively investigating additional preventive measures. We are also advising customers experiencing this type of activity to follow our general security best practices and configure an authenticated ticket creation workflow."

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In two separate reports, Apple and Samsung are said to report underwhelming sales of their new ultra-thin smartphones. According to The Elec, Apple plans to cut production of the iPhone Air while Samsung has canceled its planned Galaxy S26 Edge smartphone after disappointing sales of the Galaxy S25 Edge, Korea's NewsPim claims. MacRumors reports: Samsung apparently halted work on the Galaxy S26 Edge this week, informing employees internally that the product line would be discontinued. Internal discussions in September shifted priorities toward the more conventional "Plus" form factor after confirming that consumer demand for ultra-slim flagships was weaker than expected. [...] Samsung will apparently instead add a Galaxy S26 Plus model to its 2026 lineup, reverting to the company's traditional three-tier structure of base, Plus, and Ultra variants. Despite the cancellation, development of the Galaxy S26 Edge was already complete. Development of the S26 Plus is expected to begin before the end of the third quarter of 2025. The atmosphere inside the company is said to be "chaotic" and "embarrassed" following the sudden lineup revision. Samsung reportedly plans to sell through existing inventory of the Galaxy S25 Edge and cease further production once stock is depleted. As for Apple's iPhone Air, here's what MacRumors is reporting: The Japanese investment banking and securities firm claims that the iPhone 17 Pro and iPhone 17 Pro Max are seeing higher sales than their predecessors during the same period last year, while the standard iPhone 17 is a major success, performing significantly better than the iPhone 16. The iPhone Air is apparently the outlier; Apple plans to reduce production by one million units this year. Meanwhile, Apple plans to increase production of all other models by two million units. The overall production forecast of the iPhone 17 series this year has also been increased from 88 million units to 94 million units for the start of 2026.

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A network of classified Starshield satellites built by SpaceX for the U.S. government is transmitting signals on radio frequencies reserved for Earth-to-space commands. According to NPR, it may violate international standards. From the report: Satellites associated with the Starshield satellite network appear to be transmitting to the Earth's surface on frequencies normally used for doing the exact opposite: sending commands from Earth to satellites in space. The use of those frequencies to "downlink" data runs counter to standards set by the International Telecommunication Union, a United Nations agency that seeks to coordinate the use of radio spectrum globally. Starshield's unusual transmissions have the potential to interfere with other scientific and commercial satellites, warns Scott Tilley, an amateur satellite tracker in Canada who first spotted the signals. "Nearby satellites could receive radio-frequency interference and could perhaps not respond properly to commands -- or ignore commands -- from Earth," he told NPR. Outside experts agree there's the potential for radio interference. "I think it is definitely happening," said Kevin Gifford, a computer science professor at the University of Colorado, Boulder who specializes in radio interference from spacecraft. But he said the issue of whether the interference is truly disruptive remains unresolved. [...] Tilley says he's detected signals from 170 of the Starshield satellites so far. All appear in the 2025-2110 MHz range, though the precise frequencies of the signals move around.

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An anonymous reader quotes a report from The Conversation: When teachers rely on commonly used artificial intelligence chatbots to devise lesson plans, it does not result in more engaging, immersive or effective learning experiences compared with existing techniques, we found in our recent study. The AI-generated civics lesson plans we analyzed also left out opportunities for students to explore the stories and experiences of traditionally marginalized people. The allure of generative AI as a teaching aid has caught the attention of educators. A Gallup survey from September 2025 found that 60% of K-12 teachers are already using AI in their work, with the most common reported use being teaching preparation and lesson planning. [...] For our research, we began collecting and analyzing AI-generated lesson plans to get a sense of what kinds of instructional plans and materials these tools provide to teachers. We decided to focus on AI-generated lesson plans for civics education because it is essential for students to learn productive ways to participate in the U.S. political system and engage with their communities. To collect data for this study, in August 2024 we prompted three GenAI chatbots -- the GPT-4o model of ChatGPT, Google's Gemini 1.5 Flash model and Microsoft's latest Copilot model -- to generate two sets of lesson plans for eighth grade civics classes based on Massachusetts state standards. One was a standard lesson plan and the other a highly interactive lesson plan. We garnered a dataset of 311 AI-generated lesson plans, featuring a total of 2,230 activities for civic education. We analyzed the dataset using two frameworks designed to assess educational material: Bloom's taxonomy and Banks' four levels of integration of multicultural content. Bloom's taxonomy is a widely used educational framework that distinguishes between "lower-order" thinking skills, including remembering, understanding and applying, and "higher-order" thinking skills -- analyzing, evaluating and creating. Using this framework to analyze the data, we found 90% of the activities promoted only a basic level of thinking for students. Students were encouraged to learn civics through memorizing, reciting, summarizing and applying information, rather than through analyzing and evaluating information, investigating civic issues or engaging in civic action projects. When examining the lesson plans using Banks' four levels of integration of multicultural content model (PDF), which was developed in the 1990s, we found that the AI-generated civics lessons featured a rather narrow view of history -- often leaving out the experiences of women, Black Americans, Latinos and Latinas, Asian and Pacific Islanders, disabled individuals and other groups that have long been overlooked. Only 6% of the lessons included multicultural content. These lessons also tended to focus on heroes and holidays rather than deeper explorations of understanding civics through multiple perspectives. Overall, we found the AI-generated lesson plans to be decidedly boring, traditional and uninspiring. If civics teachers used these AI-generated lesson plans as is, students would miss out on active, engaged learning opportunities to build their understanding of democracy and what it means to be a citizen.

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A potential tragedy was narrowly averted at a Wikipedia conference in Manhattan when two volunteer editors tackled an armed man who stormed the stage and threatened to kill himself during a keynote speech (source paywalled; alternative source). The gunman, who claimed he was protesting Wikipedia's policy banning self-identified pedophiles, was disarmed and taken into custody after community members swiftly intervened. The New York Times reports: The armed man came striding up the aisle at a conference for Wikipedia editors Friday morning in Manhattan, several witnesses said. The man, draped in a multicolored flag, walked onto the stage and stood next to Maryana Iskander, the chief of the nonprofit group that runs Wikipedia, interrupting her speech. He announced that he was going to kill himself. He held a gun near his head and pointed it toward the ceiling. The audience of well over a hundred people panicked. "People started yelling, 'Get down, get down!' and people started ducking behind their chairs," said Bill Adair, a journalism professor who was there and is writing a book on Wikipedia. A man in an orange sweatshirt rushed the stage. He was not in law enforcement, but a Wikipedia contributor on the conference's "trust and safety team": Richard Knipel, the City University of New York's "Wikimedian-in-residence." He grabbed the gunman from behind. Another Wikipedian on the trust and safety team, Andrew Lih, had been standing watch in the aisle and charged forward, too. "I saw the gun he's holding go from pointing up at the ceiling to sweeping down toward the room, and as it swept across me I said 'Oh, my god,' and I ducked down, but I still kept moving" said Mr. Lih, a digital strategist who works with museums and libraries. "I grabbed his arm," he continued. "He was still clutching his gun pretty hard. I pried his fingers away from it, removed it from his hands and put it down." The gun was loaded, according to a senior law enforcement official who spoke on the condition of anonymity to discuss a pending investigation. In seconds, a potential scene of bloodshed had been averted, a life may have been saved, and two volunteer editors of an online encyclopedia had become unlikely heroes.

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Amazon is investing hundreds of millions into the Cascade Advanced Energy Facility, a next-generation small modular reactor project in Richland, Washington, developed with X-energy and Energy Northwest. "The question now is will it be enough to kick off a new wave of U.S. nuclear energy innovation -- a field that America largely soured on by the 1980s?" writes GeekWire. From the report: The facility will be located near Richland, Wash., near Energy Northwest's Columbia Generating Station nuclear plant. The initial goal is to install a cluster of four small modular reactors (SMRs) that can produce up to 320 megawatts of power, but the overall vision is to construct 12 reactors total, with a capacity of nearly one gigawatt. If all the funding, permitting and public support come together, construction should start within the next five years, with the plant coming online in the 2030s. [...] For Amazon, its support of the Cascade Advanced Energy Facility is part of a much bigger initiative. The company has set a goal of deploying 5 gigawatts of nuclear power in the U.S. by 2039. "One thing that Amazon does well is scale technology," said Brandon Oyer, Amazon Web Services' head of power and water for North and South America. "We've done this over and over again ... We'll go and make an investment and then learn how to scale that up, drive out cost, make it more readily available." Targeting SMRs for amplification was a "natural fit," Oyer added. The company believes nuclear aligns with its climate ambitions. Amazon matches all of its electricity use with clean power and is the largest corporate purchaser of wind, solar and other renewable sources. That said, it is struggling to cut its carbon footprint to reach a goal of net-zero emissions by 2040 as the AI-boom stokes energy use. Amazon reported that its carbon footprint grew by 6% last year. Amazon has dibs on half of the 320 megawatts of electricity that will be generated by the first four reactors at the Washington site, but will take all of it if the power prices are too high for local utilities to afford. Cullen said that if everything goes well with the initial phase, it would be straightforward to build the other eight reactors as the permits will encompass the complete build out. The added reactors would produce enough electricity for about one million homes and should come at a lower cost. "Amazon recognizes the role they can -- and are willing -- to play," Cullen said. The company can take some of the early risk and bring that catalytic capital, he said, which is "every, very difficult for utilities to do."

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Hackers breached financial services firm Prosper, stealing the personal data of roughly 17.6 million people, including Social Security numbers, income details, and government IDs. "We have evidence that confidential, proprietary, and personal information, including Social Security Numbers, was obtained, including through unauthorized queries made on Company databases that store customer information and applicant data. We will be offering free credit monitoring as appropriate after we determine what data was affected," the company says. "The investigation is still in its very early stages, but resolving this incident is our top priority and we are committed to sharing additional information with our customers as appropriate." BleepingComputer reports: Prosper operates as a peer-to-peer lending marketplace that has helped over 2 million customers secure more than $30 billion in loans since its founding in 2005. As the company disclosed one month ago on a dedicated page, the breach was detected on September 2, but Prosper has yet to find evidence that the attackers gained access to customer accounts and funds. However, the attackers stole data belonging to Prosper customers and loan applicants. The company hasn't shared what information was exposed beyond Social Security numbers because it's still investigating what data was affected. Prosper added that the security breach didn't impact its customer-facing operations and that it has reported the incident to relevant authorities and is collaborating with law enforcement to investigate the attack. [...] The stolen information also includes customers' names, government-issued IDs, employment status, credit status, income levels, dates of birth, physical addresses, IP addresses, and browser user agent details. Have I Been Pwned revealed the extent of the incident on Thursday.

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An anonymous reader quotes a report from The Register: Hyperscale datacenters stateside will consume 22 percent more grid power by the end of 2025 than a year ago, and are forecast to need nearly three times as much electricity by the end of the decade. Warnings about datacenters' rising energy draw are coming thick and fast of late, and this latest one from 451 Research (now a part of S&P Global) comes with figures and cautions about how fast this change may occur and what grid resources will be required to meet it. The bit barn building boom is largely fueled by estimated demand for new machine learning models, which require highly configured servers packed with power-hungry GPUs to develop and train. The power and cooling infrastructure required also mean it is easier to build a new facility rather than attempt to retrofit an existing one. As a consequence, utility power to datacenters in America is estimated to jump 11.3 GW to 61.8 GW by the end of this year. 451 calculates this will rise again to 75.8 GW in 2026, then 108 GW in 2028, before hitting 134.4 GW by 2030. These figures also exclude enterprise-owned facilities, only considering those of the hyperscale tech giants such as Amazon, Apple, Google, Meta, and Microsoft, alongside leased and crypto-mining sites. The research identifies Virginia and Texas as the two states with by far the highest requirement for bit barn energy supplies in the US this year. 451 forecasts that Virginia's datacenter load, made up of leased and hyperscale facilities, will reach 12.1 GW in 2025, up from 9.3 GW last year. In Texas, demand is driven by cryptomining and leased capacity, and is slated to hit 9.7 GW this year, from less than 8 GW previously. However, the search for an optimum location is seeing datacenter operators explore emerging markets such as Idaho, Louisiana, Oklahoma and smaller cities in West Texas, looking for "stranded power" and alternative energy generation opportunities, the report says.

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Apple has struck a five-year, $750 million deal to become the exclusive U.S. home for Formula 1 starting in 2026. "Apple is paying a significant premium over the $90 million per year currently paid by ESPN, whose F1 broadcast deal expires at the end of 2025 after holding the rights in the U.S. since 2018," notes Variety. From the report: According to Apple, it will deliver the Formula 1 programming with a "more dynamic and elevated viewing experience," and both parties expressed optimism that the deal will attract new motorsports fans in America in the years ahead. The company is rebranding the video-streaming service, which launched in 2019 as Apple TV+, to remove the plus sign. It's another big move by Apple into sports, which also has streaming deals with MLB and Major League Soccer. The F1 agreement and follows Apple's partnership with Formula 1 for original film "F1 The Movie," starring Brad Pitt, which raked in $629 million worldwide at the box office this year -- the highest-grossing sports movie of all time and Pitt's highest-grossing feature to date. "F1 The Movie" will debut on Apple TV on Dec. 12, 2025.

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Amazon's Ring has announced a partnership with Flock Safety, the AI-powered camera network already used by ICE, the Secret Service, and other federal agencies. "Now agencies that use Flock can request that Ring doorbell users share footage to help with 'evidence collection and investigative work,'" reports TechCrunch. From the report: Flock cameras work by scanning the license plates and other identifying information about cars they see. Flock's government and police customers can also make natural language searches of their video footage to find people who match specific descriptions. However, AI-powered technology used by law enforcement has been proven to exacerbate racial biases. On the same day that Ring announced this partnership, 404 Media reported that ICE, the Secret Service, and the Navy had access to Flock's network of cameras. By partnering with Ring, Flock could potentially access footage from millions more cameras.

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An anonymous reader quotes a report from Ars Technica: Texas is being sued by a Big Tech lobby group over the state's new law that will require app stores to verify users' ages and impose restrictions on users under 18. "The Texas App Store Accountability Act imposes a broad censorship regime on the entire universe of mobile apps," the Computer & Communications Industry Association (CCIA) said yesterday in a lawsuit (PDF). "In a misguided attempt to protect minors, Texas has decided to require proof of age before anyone with a smartphone or tablet can download an app. Anyone under 18 must obtain parental consent for every app and in-app purchase they try to download -- from ebooks to email to entertainment." The CCIA said in a press release that the law violates the First Amendment by imposing "a sweeping age-verification, parental consent, and compelled speech regime on both app stores and app developers." When app stores determine that a user is under 18, "the law prohibits them from downloading virtually all apps and software programs and from making any in-app purchases unless their parent consents and is given control over the minor's account," the CCIA said. "Minors who are unable to link their accounts with a parent's or guardian's, or who do not receive permission, would be prohibited from accessing app store content." The law requires app developers "to 'age-rate' their content into several subcategories and explain their decision in detail," and "notify app stores in writing every time they improve or modify the functions, features, or user experience of their apps," the group said. The lawsuit says the age-rating system relies on a "vague and unworkable set of age categories." "Our Constitution forbids this," the lawsuit said. "None of our laws require businesses to 'card' people before they can enter bookstores and shopping malls. The First Amendment prohibits such oppressive laws as much in cyberspace as it does in the physical world." The lawsuit was filed in US District Court for the Western District of Texas. CCIA members include Apple and Google, which have both said the law would reduce privacy for app users. The companies recently described their plans to comply, saying they would take steps to minimize the privacy risks.

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Scientists from Spain and China have successfully repaired the blood-brain barrier in Alzheimer's-model mice, enabling the brain to naturally clear amyloid-beta plaques and reverse cognitive decline. "After just three drug injections, mice with certain genes that mimic Alzheimer's showed a reversal of several key pathological features," adds ScienceAlert. From the report: Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in clumps of amyloid-beta plaques, a hallmark of Alzheimer's disease. The mice had previously shown signs of cognitive decline, but after all three doses, the animals performed on par with their healthy peers in spatial learning and memory tasks. The benefits lasted at least six months. These preclinical results don't guarantee success in humans, but they're an encouraging start, which the authors say "heralds a new era" in drug research. "The therapeutic implications are profound," claim the international team of researchers, co-led by scientists at the Institute for Bioengineering of Catalonia (IBEC) and the West China Hospital Sichuan University (WCHSU). The findings have been published in Signal Transduction and Targeted Therapy.

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An anonymous reader quotes a report from the Conversation: Sound waves at frequencies above the threshold for human hearing are routinely used in medical care. Also known as ultrasound, these sound waves can help clinicians diagnose and monitor disease, and can also provide first glimpses of your newest family members. And now, patients with conditions ranging from cancer to neurodegenerative diseases like Alzheimer's may soon benefit from recent advances in this technology. I am a biomedical engineer who studies how focused ultrasound -- the concentration of sound energy into a specific volume -- can be fine-tuned to treat various conditions. Over the past few years, this technology has seen significant growth and use in the clinic. And researchers continue to discover new ways to use focused ultrasound to treat disease. [...] Research on focused ultrasound has primarily focused on the most devastating and prevalent diseases, such as cancer and Alzheimer's disease. However, I believe that further developments in, and increased use of, focused ultrasound in the clinic will eventually benefit patients with rare diseases. One rare disease of particular interest for my lab is cerebral cavernous malformation, or CCM. CCMs are lesions in the brain that occur when the cells that make up blood vessels undergo uncontrolled growth. While uncommon, when these lesions grow and hemorrhage, they can cause debilitating neurological symptoms. The most common treatment for CCM is surgical removal of the brain lesions; however, some CCMs are located in brain areas that are difficult to access, creating a risk of side effects. Radiation is another treatment option, but it, too, can lead to serious adverse effects. We found that using focused ultrasound to open the blood-brain barrier can improve drug delivery to CCMs. Additionally, we also observed that focused ultrasound treatment itself could stop CCMs from growing in mice, even without administering a drug. While we don't yet understand how focused ultrasound is stabilizing CCMs, abundant research on the safety of using this technique in patients treated for other conditions has allowed neurosurgeons to begin designing clinical trials testing the use of this technique on people with CCM. With further research and advancements, I am hopeful that focused ultrasound can become a viable treatment option for many devastating rare diseases.

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mspohr shares a report from Futurism: Western automotive and green energy executives who visit China are returning humbled -- and even terrified. As The Telegraph reports, the executives are warning that the country's heavily automated manufacturing industry could quickly leave Western nations behind, especially when it comes to electric vehicles. "We are in a global competition with China, and it's not just EVs," Ford CEO Jim Farley told The Verge last month. "And if we lose this, we do not have a future at Ford." Some companies are giving up on new initiatives altogether, with the founder of mining company Fortescue, Andrew Forrest, claiming that his recent trip to China led to him abandoning attempts to produce EV powertrains in-house. "There are no people -- everything is robotic," he told The Telegraph. Other executives recalled touring "dark factories" that don't even need to keep the lights on, as most work is being done around the clock by robots. "You get this sense of a change, where China's competitiveness has gone from being about government subsidies and low wages to a tremendous number of highly skilled, educated engineers who are innovating like mad," British energy supplier Octopus CEO Greg Jackson told the newspaper. According to recent figures by the International Federation of Robotics, China has deployed orders of magnitude more industrial robots than Germany, the US, and the UK.

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Norway has effectively achieved its 2025 goal of 100% electric new car sales, prompting the government to declare "mission accomplished" and propose scaling back EV tax exemptions to reflect a mature market. "We have had a goal that all new passenger cars should be electric by 2025, and ... we can say that the goal has been achieved," announced Finance Minister Jens Stoltenberg. Electrek reports: With the finish line in sight, the Norwegian government is now fine-tuning its approach. The current incentive program maintains the crucial VAT exemption for EVs, but only up to a purchase price of 500,000 Norwegian kroner (approximately $49,000 USD). This move is designed to target more expensive, luxury EVs, ensuring that the incentive benefits a broader range of consumers. However, the latest budget proposal aims to reduce the EV tax exemption to vehicles costing 300,000 Norwegian kroner (~30,000 USD). This would apply for 2026, and then the tax exemption would completely end in 2027. Additionally, the government plans to increase taxes on new gasoline and diesel cars, further widening the cost gap between polluting and zero-emission vehicles. However, the proposal still needs to be adopted by Norway's government, and there is some opposition. EV associations are advocating for a more extended phase-out period to ensure that the adoption rate doesn't decline.

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Boris Johnson's former adviser claims that China infiltrated a key UK government data-transfer network for years, compromising highly classified materials and prompting a Whitehall cover-up that prioritized Chinese investment over national security. The Times reports: Dominic Cummings, who served as a senior adviser to Boris Johnson, said that he and the then prime minister were informed about the breach in 2020 but that there had subsequently been a cover-up. He said he was warned at the time that disclosing some specific details of the breach would be a criminal offence. He claimed that the breach included some "Strap" material, which is the government term for the highest level of classified information. The breach, which was confirmed by two other senior Whitehall sources, was said to have been connected to a Chinese-owned company involved in Britain's critical national infrastructure. Tom Tugendhat, a former Tory security minister, supported Cummings's account. Cummings said that he and Johnson were informed of the breach in the "bunker" of No 10 -- a reference to the secure room in Downing Street. He told The Times: "The cabinet secretary said, 'We have to explain something; there's been a serious problem', and he talked through what this was. "And it was so bizarre that, not just Boris, a few people in the room were looking around like this -- 'Am I somehow misunderstanding what he's saying? Because it sounds f***ing crazy.'" He added: "What I'm saying is that some Strap stuff was compromised and vast amounts of data classified as extremely secret and extremely dangerous for any foreign entity to control was compromised. "Material from intelligence services. Material from the National Security Secretariat in the Cabinet Office. Things the government has to keep secret. If they're not secret, then there are very, very serious implications for it."

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